Give me your delicious spiel
The title is a reference to the Red String of Fate, an ancient Chinese belief that people who are destined to find love and marry each other are bound by an invisible red cord. The cord can become tangled and bind with other cords, but will never break, so these cords can create a great web of fate at times. Hence why all these characters lives are interconnected and they seemingly keep running into each other even when they don't plan too.
We're seeing a snapshot of Lena and Ian's lives. Perhaps they have a red cord that binds them, or perhaps their red cords just got tangled with each other the night they met in that ally. How we play them will likely determine that, but for now they are bound by fate to at least be near each other.
As the story has progressed, many of these cords have tangled further with each other; notably Ivy, Perry, and Holly are much more interconnected with both Lena and Ian now than they were at the start of the game. Cindy was loosely connected to Ian at the start of the game, but depending on how we play could be much tighter, and with her hiring to Wild Cats she may start finding herself more closely connected to Lena moving forward as well.